Article-Journal

Analysis of cardiomyocyte clonal expansion during mouse heart development and injury

The cellular mechanisms driving cardiac tissue formation remain poorly understood, largely due to the structural and functional complexity of the heart. It is unclear whether newly …

konstantina-ioanna-sereti
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Cooperative binding of transcription factors orchestrates reprogramming

Oct4, Sox2, Klf4, and cMyc (OSKM) reprogram somatic cells to pluripotency. To gain a mechanistic understanding of their function, we mapped OSKM-binding, stage-specific …

constantinos-chronis
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Human naive pluripotent stem cells model X chromosome dampening and X inactivation

Naive human embryonic stem cells (hESCs) can be derived from primed hESCs or directly from blastocysts, but their X chromosome state has remained unresolved. Here, we show that the …

anna-sahakyan
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